RESEARCH OVERVIEW
What is Semax?
Semax is a synthetic heptapeptide commonly described in the literature as an ACTH-fragment analogue. Experimental research has examined neurotrophin expression, neuronal signalling and responses to experimentally induced brain injury. Those research areas should be described separately from claims about memory enhancement or protection against neurological disease.
Semax 10 mg — product details
This listing is for Semax 10 mg, product code JG-MIG-022. The 10 mg figure is the listed material quantity, not a recommended dose or a concentration. Review this strength’s label and matching batch record when planning a laboratory assay.
LISTED CONTENT
10 mg
PRODUCT CODE
JG-MIG-022
INTENDED USE
Laboratory research
Research focus and areas of interest
Neurotrophin gene expression
A rat study investigated changes in nerve-growth-factor and brain-derived-neurotrophic-factor gene expression. Gene-expression measurements can identify a biological response, but they do not alone establish functional recovery, a clinical benefit or a complete mechanism of action. [1]
Transcriptomic and protein responses
Experiments using rat cerebral-ischaemia models examined immune-related transcripts and proteins involved in inflammation, cell death and stress signalling. Findings depend on the sampled brain region and time point, and individual marker changes should not be presented as a universal neuroprotective effect. [2]
Neuronal calcium and experimental behaviour
Brain-slice work investigated intracellular calcium fluctuations, while a separate rat study considered behavioural and neurochemical changes following early-life drug exposure. These are specialised experimental systems with different questions and endpoints. [4]
Evidence and limitations
The selected references are primarily preclinical. They do not justify claims that this JGPEP+ vial treats stroke, improves cognition or is safe for self-administration. An ACTH-related sequence also does not imply that Semax reproduces all actions of the parent hormone.
Scientific references describe the material and methods used by their authors. They do not certify this product’s purity, sterility, identity or suitability for a particular experiment. A related analogue, delivery system or combination is not automatically equivalent to the supplied peptide.
Technical identity and documentation
Literature identity: synthetic seven-amino-acid ACTH-related peptide; the reported sequence is Met-Glu-His-Phe-Pro-Gly-Pro. Confirm sequence and chemical form in the supplied batch documentation. Manufacturing source and stability cannot be established from these papers.
For this product’s identity and batch results, visit the COA and documentation page or contact JGPEP+ with the product and batch numbers. Literature values should not replace a matching analytical certificate.
Storage and laboratory handling
Follow the product label and batch-specific supplier instructions. Confirm temperature, solvent compatibility, stability and any reconstitution requirements before use. Storage conditions reported for another supplier or a clinical formulation should not be applied automatically to this material.
Research references
Original studies and analytical papers are linked below. Study type is included so that laboratory models, clinical research and related-analogue evidence can be distinguished.
1. Neurotrophin expression in rat brain. Agapova TY et al. 2007 May 1. Neuroscience letters. Animal study. PubMed PMID 17353092 · Publisher / DOI
2. Rat cerebral-ischaemia transcriptomics. Medvedeva EV et al. 2014 Mar 24. BMC genomics. Animal transcriptomics study. PubMed PMID 24661604 · Publisher / DOI
3. Protein responses after experimental ischaemia. Sudarkina OY et al. 2021 Jun 8. International journal of molecular sciences. Animal protein-expression study. PubMed PMID 34201112 · Publisher / DOI
4. Calcium dynamics in rat neuronal preparations. Kolbaev SN et al. 2025 Aug. Bulletin of experimental biology and medicine. Ex vivo neuronal study. PubMed PMID 41171324 · Publisher / DOI
5. Behavioural and neurochemical rat experiments. Glazova NY et al. 2021 Apr. Neuropeptides. Animal study. PubMed PMID 33418449 · Publisher / DOI
For laboratory research only. Not for human or veterinary consumption or administration. This information is scientific background, not medical advice or an administration guide.
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