RESEARCH OVERVIEW
What is IGF-1 LR3?
IGF-1 LR3, also called Long R3 IGF-I, is a modified analogue used in research on insulin-like-growth-factor signalling. Changes relative to native IGF-I affect its interaction with binding proteins, making the exact analogue and experimental environment important when interpreting receptor or cell-growth studies.
IGF-1 LR3 1 mg — product details
This listing is for IGF-1 LR3 1 mg, product code JG-MIG-036. The 1 mg figure is the listed material quantity, not a recommended dose or a concentration. Review this strength’s label and matching batch record when planning a laboratory assay.
LISTED CONTENT
1 mg
PRODUCT CODE
JG-MIG-036
INTENDED USE
Laboratory research
Research focus and areas of interest
Production and cell-bioactivity research
A recombinant-expression study investigated the production and characterisation of IGF-I and LR3 IGF-I using a microbial expression system. Its bioactivity measurements concern the investigators’ purified preparations, not the manufacturing process or assay performance of this catalogue item. [1]
Binding proteins and tissue development
An in vitro bovine-follicle study compared LR3 with other IGF-I exposures, while fetal-sheep work examined insulin-secretion responses. These studies show how binding-protein context, exposure duration and the experimental tissue affect interpretation. [2]
Receptor and vascular models
Other experiments used Long R3 IGF-I to investigate vascular-cell phenotype or to distinguish IGF-binding-protein-dependent effects from other mechanisms. In such papers, LR3 may be an experimental tool rather than the principal subject of the study. [4]
Evidence and limitations
The references include cell culture, tissue-development and animal models. They do not establish a muscle-building indication, a human treatment protocol or the safety of external administration. Results for native IGF-I cannot be transferred wholesale to the LR3 analogue.
Scientific references describe the material and methods used by their authors. They do not certify this product’s purity, sterility, identity or suitability for a particular experiment. A related analogue, delivery system or combination is not automatically equivalent to the supplied peptide.
Technical identity and documentation
Literature identity: the Long R3 analogue of IGF-I. Request sequence, folding and disulfide information, chemical identity and batch-specific activity data where relevant. Do not infer recombinant production or validated bioactivity for this product from another laboratory’s production paper.
For this product’s identity and batch results, visit the COA and documentation page or contact JGPEP+ with the product and batch numbers. Literature values should not replace a matching analytical certificate.
Storage and laboratory handling
Follow the product label and batch-specific supplier instructions. Confirm temperature, solvent compatibility, stability and any reconstitution requirements before use. Storage conditions reported for another supplier or a clinical formulation should not be applied automatically to this material.
Research references
Original studies and analytical papers are linked below. Study type is included so that laboratory models, clinical research and related-analogue evidence can be distinguished.
1. Recombinant expression and bioactivity comparison. Lu Z et al. 2023 Jul. Applied microbiology and biotechnology. Production and cell-assay study. PubMed PMID 37261455 · Publisher / DOI
2. LR3 and binding proteins in bovine follicle culture. Thomas FH et al. 2007 Jun. Reproduction (Cambridge, England). Ex vivo tissue-culture study. PubMed PMID 17636166 · Publisher / DOI
3. Acute LR3 exposure in a fetal-sheep model. White A et al. 2023 Jun. Journal of developmental origins of health and disease. Animal and isolated-islet study. PubMed PMID 37114757 · Publisher / DOI
4. Long R3 use in vascular-cell and mouse research. von der Thüsen JH et al. 2011 Feb. The American journal of pathology. Cell and animal study. PubMed PMID 21281823 · Publisher / DOI
5. LR3 as a comparator in binding-protein experiments. Liu B et al. 2007 Mar 15. Oncogene. Cell and animal mechanistic study. PubMed PMID 16983336 · Publisher / DOI
For laboratory research only. Not for human or veterinary consumption or administration. This information is scientific background, not medical advice or an administration guide.
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